Article
The role of UDP-Glc:glycoprotein glucosyltransferase 1 in the maturation of an obligate substrate prosaposin.
The Journal of cell biology - 31 May 2010
Pearse Bradley R, Tamura Taku, Sunryd Johan C, Grabowski Gregory A, Kaufman Randal J, Hebert Daniel N
Abstract excerpt
An endoplasmic reticulum (ER) quality control system assists in efficient folding and disposal of misfolded proteins. N-linked glycans are critical in these events because their composition dictates interactions with molecular chaperones. UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) is a...
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