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Article

Development and characterization of a conditional mitochondrial complex I assembly system.

The Journal of biological chemistry - 26 Mar 2004

Yadava Nagendra, Houchens Toby, Potluri Prasanth, Scheffler Immo E

Abstract excerpt

We developed a conditional complex I assembly system in a Chinese hamster fibroblast mutant line, CCL16-B2, that does not express the NDUFA1 gene (encoding the MWFE protein). In this mutant, a hemagglutinin (HA) epitope-tagged MWFE protein was expressed from a doxycycline-inducible promoter. The expression of the protein was absolutely dependent on the presence of doxycycline, and the gene could be turned off...

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Source

Identifiers

PMID: 14722084
DOI: 10.1074/jbc.M313588200

Genes

CCL16
NDUFA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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