Article
Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process.
Molecular genetics and genomics : MGG - 1 Aug 2008
Remacle Claire, Barbieri M Rosario, Cardol Pierre, Hamel Patrice P
Abstract excerpt
With more than 40 subunits, one FMN co-factor and eight FeS clusters, complex I or NADH:ubiquinone oxidoreductase is the largest multimeric respiratory enzyme in the mitochondria. In this review, we focus on the diversity of eukaryotic complex I. We describe the additional activities that have been reported to be associated with mitochondrial complex I and discuss their physiological significance. The recent...
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