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Article

The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis.

Human molecular genetics - 1 Oct 2014

Zurita Rendón Olga, Silva Neiva Lissiene, Sasarman Florin, Shoubridge Eric A

Abstract excerpt

Complex I of the mitochondrial respiratory chain is a large multisubunit enzyme that assembles from nuclear and mtDNA-encoded components. Several complex I assembly factors have been identified, but their precise functions are not well understood. Here, we have investigated the function of one of these, NDUFAF7, a soluble matrix protein comprised of a DUF185 domain that harbors a methyltransferase motif....

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Topics

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Share to Electron Transport Complex I
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NADH Dehydrogenase

Share to Protein Interaction Domains and Motifs

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Source

Open in PubMed Open full text

Identifiers

PMID: 24838397
DOI: 10.1093/hmg/ddu239
PMCID: PMC4159157

Genes

NDUFAF7
NDUFS2
NDUFA9
NDUFS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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