Article
Molecular genetics of the mammalian NADH-ubiquinone oxidoreductase.
Journal of bioenergetics and biomembranes - 1 Jun 2001
Scheffler I E, Yadava N
Abstract excerpt
A serendipitous observation led to the first characterization of a respiration-deficient Chinese hamster mutant cell line. It has guided the design of an enrichment scheme for the isolation of additional mutant cell lines. Several complementation groups were identified with mutations affecting complex I. The X-linked NDUFA1 gene encoding the MWFE protein represents one group. Several mutant alleles isolated...
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