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Article

An evolutionary route to xylanase process fitness.

Protein science : a publication of the Protein Society - 1 Feb 2004

Palackal Nisha, Brennan Yali, Callen Walter N, Dupree Paul, Frey Gerhard, Goubet Florence, Hazlewood Geoffrey P, Healey Shaun, Kang Young E, Kretz Keith A, Lee Edd, Tan Xuqiu, Tomlinson Geoffery L, Verruto John, Wong Vicky W K, Mathur Eric J, Short Jay M, Robertson Dan E, Steer Brian A

Abstract excerpt

Directed evolution technologies were used to selectively improve the stability of an enzyme without compromising its catalytic activity. In particular, this article describes the tandem use of two evolution strategies to evolve a xylanase, rendering it tolerant to temperatures in excess of 90 deg...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14718652
DOI: 10.1110/ps.03333504
PMCID: PMC2286715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14718652-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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