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Article

Unleashing the Power of Evolution in Xylanase Engineering: Investigating the Role of Distal Mutation Regulation.

Journal of agricultural and food chemistry - 14 Aug 2024

Wu Ya, Yang Yu, Lu Gen, Xiang Wan-Lu, Sun Tian-Yu, Chen Ke-Wei, Lv Xiang, Gui Yi-Fan, Zeng Rui-Qi, Du Yi-Kai, Fu Chun-Hua, Huang Jian-Wen, Chen Chun-Chi, Guo Rey-Ting, Yu Long-Jiang

Abstract excerpt

The drive to enhance enzyme performance in industrial applications frequently clashes with the practical limitations of exhaustive experimental screening, underscoring the urgency for more refined and strategic methodologies in enzyme engineering. In this study, xylanase Xyl-1 was used as the model, coupling evolutionary insights with energy functions to obtain theoretical potential mutants, which were...

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Identifiers

PMID: 39082219
DOI: 10.1021/acs.jafc.4c03245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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