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Article

Store-Operated Calcium Entry through Orai Is Required for Transcriptional Maturation of the Flight Circuit in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 Oct 2015

Pathak Trayambak, Agrawal Tarjani, Richhariya Shlesha, Sadaf Sufia, Hasan Gaiti

Abstract excerpt

Store operated calcium entry (SOCE) is thought to primarily regulate calcium homeostasis in neurons. Subsequent to identification of Orai as the SOCE channel in nonexcitable cells, investigation of Orai function in neurons demonstrated a requirement for SOCE in Drosophila flight. Here, by analysis of an Orai mutant and by controlled expression of a dominant-negative Drosophila Orai transgene, we show that...

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Share to Acetyl-CoA Carboxylase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26446229
DOI: 10.1523/JNEUROSCI.1680-15.2015
PMCID: PMC6605383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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