Article
Calcyclin-binding protein/Siah-1-interacting protein as a regulator of transcriptional responses in brain cells.
Journal of neuroscience research - 1 Jan 2015
Kilanczyk Ewa, Filipek Anna, Hetman Michal
Abstract excerpt
The calcyclin-binding protein/Siah-1-interacting protein (CacyBP/SIP) is highly expressed in the brain and has been shown to regulate β-catenin-driven transcription in thymocytes. Therefore, we investigated whether CacyBP/SIP plays a role as a transcriptional regulator in brain cells. In brain-derived neurotrophic factor (BDNF)- and forskolin-stimulated rat primary cortical neurons, overexpression of CacyBP/SIP...
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