Article
Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses.
Proceedings of the National Academy of Sciences of the United States of America - 27 Jan 2004
Kuwahara Kazuhiko, Fujimura Satoru, Takahashi Yoshimasa, Nakagata Naomi, Takemori Toshitada, Aizawa Shinichi, Sakaguchi Nobuo
Abstract excerpt
Acquired immunity depends on proliferation and differentiation of antigen (Ag)-specific B cells in germinal centers (GCs) of lymphoid follicles in response to T cell-dependent Ags. Here, we studied the function of GC-associated nuclear protein that is selectively up-regulated in GC-B cells. B cel...
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