Role of Rho-kinase in maintaining airway smooth muscle contractile phenotype.

Abstract excerpt

This study aims to investigate the role of Rho-kinase in phenotype switching and proliferation of bovine tracheal smooth muscle. To induce different phenotypic states, bovine tracheal smooth muscle strips were cultured (8 days) in 10% foetal bovine serum (foetal bovine serum, less contractile phenotype) or insulin (1 microM, hypercontractile phenotype) and compared to strips cultured in serum-free medium. In...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bronchodilator Agents
• Share to Isometric Contraction