Article
A role for rho in smooth muscle phenotypic regulation.
Annals of the New York Academy of Sciences - 1 Dec 2001
Worth N F, Campbell G R, Rolfe B E
Abstract excerpt
The role of the small GTP-binding protein Rho in the process of smooth muscle cell (SMC) phenotypic modulation was investigated using cultured rabbit aortic SMCs. Both Rho transcription and Rho protein expression were high for the first 3 days of culture ("contractile" state cells), with expression decreasing after change to the "synthetic" state and peaking upon return to the contractile phenotype. Activation of...
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