Article
Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis.
The Journal of biological chemistry - 12 Mar 2004
Baba Suzie W, Belogrudov Grigory I, Lee Justine C, Lee Peter T, Strahan Jeff, Shepherd Jennifer N, Clarke Catherine F
Abstract excerpt
Coenzyme Q (Q) functions in the electron transport chain of both prokaryotes and eukaryotes. The biosynthesis of Q requires a number of steps involving at least eight Coq polypeptides. Coq5p is required for the C-methyltransferase step in Q biosynthesis. In this study we demonstrate that Coq5p is peripherally associated with the inner mitochondrial membrane on the matrix side. Phenotypic characterization of a...
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