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Article

Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants.

Biochimica et biophysica acta - 4 Apr 2014

He Cuiwen H, Xie Letian X, Allan Christopher M, Tran Uyenphuong C, Clarke Catherine F

Abstract excerpt

Coenzyme Q biosynthesis in yeast requires a multi-subunit Coq polypeptide complex. Deletion of any one of the COQ genes leads to respiratory deficiency and decreased levels of the Coq4, Coq6, Coq7, and Coq9 polypeptides, suggesting that their association in a high molecular mass complex is required for stability. Over-expression of the putative Coq8 kinase in certain coq null mutants restores steady-state levels...

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PMID: 24406904
DOI: 10.1016/j.bbalip.2013.12.017
PMCID: PMC3959571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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