Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genghis Khan (Gek) as a putative effector for <i>Drosophila</i> Cdc42 and regulator of actin polymerization

25 Nov 1997

Abstract excerpt

The small GTPases Cdc42 and Rac regulate a variety of biological processes, including actin polymerization, cell proliferation, and JNK/mitogen-activated protein kinase activation, conceivably via distinct effectors. Whereas the effector for mitogen-activated protein kinase activation appears to be p65PAK, the identity of effector(s) for actin polymerization remains unclear. We have found a putative effector for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Cellular Mechanics and Interactions
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9371783
DOI: 10.1073/pnas.94.24.12963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genghis Khan (Gek) as a putative effector for <i>Drosophila</i> Cdc42 and regulator of actin polymerizationPMID 9371783Read ↗

Identification of functional domains within the septation initiation network kinase, Cdc7.Semantic proximity Read ↗

GTPase-activating proteins for Cdc42.Semantic proximity Read ↗

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf 1Semantic proximity Read ↗

Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway.Semantic proximity Read ↗

MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development.Semantic proximity Read ↗

Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site.Semantic proximity Read ↗

A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development.Semantic proximity Read ↗

Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Semantic proximity Read ↗

Regulation of the Rac GTPase pathway by the multifunctional Rho GEF Pebble is essential for mesoderm migration in the Drosophila gastrula.Semantic proximity Read ↗

Drf1, a novel regulatory subunit for human Cdc7 kinaseSemantic proximity Read ↗

Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin PolymerizationSemantic proximity Read ↗

New Features Surrounding the Cdc42-Ste20 Module that Regulates MAP Kinase Signaling in YeastSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.