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Article

[Inhibition of mutant p53 in hepatocellular carcinoma cells by hammerhead ribozyme].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Dec 2003

Kong Xin-juan, Lin Ju-sheng, Song Yu-hu, Shen Xia, Jin You-xin

Abstract excerpt

OBJECTIVES: To investigate the inhibition of mutant type p53 in hepatocellular carcinoma by hammerhead ribozyme in both cell-free system and MHCC97 cells. METHODS: Hammerhead ribozyme genes (RZ) and control ribozyme (asRZ) directed against mutant p53 (249 codons, AGG --> AGT) were designed by com...

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Share to Cell Line, Tumor
Share to AGT gene
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Therapy

Share to Liver Neoplasms

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Share to RNA, Catalytic

Source

Identifiers

PMID: 14697131

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14697131-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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