Article
[p53 gene expression of human hepatoma cell lines and their sensitivities to parvovirus H-1].
Shi yan sheng wu xue bao - 1 Mar 1999
Guo L P, Li G D, Xu H, Huang Q S, Lin W M, Ling W H, Huang H, Luo Z Y, Su Z Z
Abstract excerpt
DNA structure and expression of p53 gene in human hepatoma cell lines SMMC-7721, YY-8103 and a spontaneously transformed liver cell line L-02 were analysed using the following method: analysis of allelic losses on chromosome 17p, PCR/SSCP, Northern blot and immunoprecipitation. There was no point mutation found in the exons 4-9 of the p53 gene, and a low level of expression of p53 gene was detected in the three...
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