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Isolation and genome sequencing of individual circulating tumor cells using hydrogel encapsulation and laser capture microdissection.

Lab on a chip - 12 Jun 2018

Park Emily S, Yan Justin P, Ang Richard A, Lee Jeong Hyun, Deng Xiaoyan, Duffy Simon P, Beja Kevin, Annala Matti, Black Peter C, Chi Kim N, Wyatt Alexander W, Ma Hongshen

Abstract excerpt

Circulating tumor cells (CTCs) are malignant cells released into the bloodstream with the potential to form metastases in secondary sites. These cells, acquired non-invasively, represent a sample of highly relevant tumor tissue that is an alternative to difficult and low-yield tumor biopsies. In recent years, there has been growing interest in genomic profiling of CTCs to enable longitudinal monitoring of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29762619
DOI: 10.1039/c8lc00184g

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ATR
FANCC
FOXA1
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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