Article
Copy Number Variation Analysis by Array Analysis of Single Cells Following Whole Genome Amplification.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Dimitriadou Eftychia, Zamani Esteki Masoud, Vermeesch Joris Robert
Abstract excerpt
Whole genome amplification is required to ensure the availability of sufficient material for copy number variation analysis of a genome deriving from an individual cell. Here, we describe the protocols we use for copy number variation analysis of non-fixed single cells by array-based approaches following single-cell isolation and whole genome amplification. We are focusing on two alternative protocols, an...
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