Article
Genotypic analysis of pulmonary Langerhans cell histiocytosis.
Human pathology - 1 Dec 2003
Dacic S, Trusky C, Bakker A, Finkelstein S D, Yousem S A
Abstract excerpt
Reported studies show that the systemic form of Langerhans cell histiocytosis (LCH) is a clonal expansion of Langerhans cells (LC) associated with aberrant expression of several oncogenes or tumor-suppressor genes. LCH of the lung is a heterogenous group of lesions thought to be a reactive rather than neoplastic process. The histogenesis of the LCH of the lung is uncertain, and to date there are no studies...
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