Article
Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations.
AIDS research and human retroviruses - 1 May 2003
Taylor Stephen, Cane Patricia, Hué Stéphane, Xu Li, Wrin Terri, Lie Yolanda, Hellmann Nicholas, Petropoulos Christos, Workman Judith, Ratcliffe Daina, Choudhury Bhudipa, Pillay Deenan
Abstract excerpt
We have investigated a potential transmission chain of HIV-1 with drug resistance-associated mutations between three individuals over a period of 5 years by use of cloning and sequencing of viral genes, and phenotypic characterization. Viruses containing reverse transcriptase drug resistance-associated mutations were transmitted sequentially between three homosexual men (A, B, and C), and persisted in one...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
