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Article

Effect of a single mutation in neuraminidase on the properties of Influenza B virus isolates.

Archives of virology - 1 Jan 2004

Katinger D, Romanova J, Ferko B, Fekete H, Egorov A

Abstract excerpt

Two strains of Influenza B virus were isolated in Vero cells. Subclones with improved efficiency of plaque formation were selected. The activity of the neuraminidase (NA) of the two subclones compared to their respective isolates dropped 20- and 100-fold, respectively. Both subclones had a common mutation in segment 6 leading to a change from Asp to Asn at position 457 in the NA. This mutation destroyed a salt...

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Identifiers

PMID: 14689282
DOI: 10.1007/s00705-003-0203-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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