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Article

Passage in Vero cells alters the characteristics of measles AIK-C vaccine strain.

Vaccine - 13 Feb 2006

Uejima Hajime, Nakayama Tetsuo, Komase Katsuhiro

Abstract excerpt

Objective of this study is to evaluate the feasibility of measles vaccine production in Vero cell culture. We constructed the full-length cDNA, pIC-MVAIK-F278Leu (small plaque-type) and pIC-MVAIK-F278Phe (large plaque-type) from the AIK-C measles vaccine strain attenuated from the Edmonston wild-type. MVAIK-S/B2 was rescued from pIC-MVAIK-F278Leu after two passages in B95a cells and MVAIK-SL/B2V1 was obtained...

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Identifiers

PMID: 16176848
DOI: 10.1016/j.vaccine.2005.08.082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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