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Article

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.

Nature cell biology - 1 Jan 2004

Nishiwaki Kiyoji, Kubota Yukihiko, Chigira Yuko, Roy Samir Kumar, Suzuki Maho, Schvarzstein Mara, Jigami Yoshifumi, Hisamoto Naoki, Matsumoto Kunihiro

Abstract excerpt

In the nematode Caenorhabditis elegans, the gonad acquires two U-shaped arms through the directed migration of its distal tip cells (DTCs), which are located at the tip of the growing gonad arms. A member of the ADAM (a disintegrin and metalloprotease) family, MIG-17, regulates directional migration of DTCs: MIG-17 is synthesized and secreted from the muscle cells of the body wall, and diffuses to the gonad where...

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PMID: 14688791
DOI: 10.1038/ncb1079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.PMID 14688791Read ↗

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