Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The secreted AdamTS-A metalloprotease is required for collective cell migration.

Development (Cambridge, England) - 1 May 2013

Ismat Afshan, Cheshire Alan M, Andrew Deborah J

Abstract excerpt

Members of the ADAMTS family of secreted metalloproteases play crucial roles in modulating the extracellular matrix (ECM) in development and disease. Here, we show that ADAMTS-A, the Drosophila ortholog of human ADAMTS 9 and ADAMTS 20, and of C. elegans GON-1, is required for cell migration during embryogenesis. AdamTS-A is expressed in multiple migratory cell types, including hemocytes, caudal visceral mesoderm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to Cell Polarity
Share to Cell Shape

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Development

Share to Hemocytes

Share to Mesoderm

Share to Salivary Glands

Share to Trachea

Source

Open in PubMed Open full text

Identifiers

PMID: 23536567
DOI: 10.1242/dev.087908
PMCID: PMC3631971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The secreted AdamTS-A metalloprotease is required for collective cell migration.PMID 23536567Read ↗

Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

bHLH transcription factors regulate organ morphogenesis via activation of an ADAMTS protease in C. elegans.Semantic proximity Read ↗

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.Semantic proximity Read ↗

The Caenorhabditis elegans ADAMTS family gene adt-1 is necessary for morphogenesis of the male copulatory organs.Semantic proximity Read ↗

Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans.Semantic proximity Read ↗

Emerging roles for ADAMTS5 during development and disease.Semantic proximity Read ↗

The novel secreted factor MIG-18 acts with MIG-17/ADAMTS to control cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C. elegans.Semantic proximity Read ↗

The extracellular metalloprotease AdamTS-A anchors neural lineages in place within and preserves the architecture of the central nervous system.Semantic proximity Read ↗

Tissue architecture in the Caenorhabditis elegans gonad depends on interactions among fibulin-1, type IV collagen and the ADAMTS extracellular protease.Semantic proximity Read ↗

MADD-4 is a secreted cue required for midline-oriented guidance in Caenorhabditis elegans.Semantic proximity Read ↗

A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.