Article
The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans.
Development (Cambridge, England) - 1 Jan 2006
Kubota Yukihiko, Sano Mitsue, Goda Saori, Suzuki Norio, Nishiwaki Kiyoji
Abstract excerpt
In C. elegans, the gonad acquires two U-shaped arms through directed migration of gonadal distal tip cells (DTCs). A member of the ADAM (a disintegrin and metalloprotease) family, MIG-17, is secreted from muscle cells and localizes to the gonadal basement membrane where it functions in DTC migrat...
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