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Article

Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans.

PloS one - 1 Jan 2020

Imanishi Ayaka, Aoki Yuma, Kakehi Masaki, Mori Shunsuke, Takano Tomomi, Kubota Yukihiko, Kim Hon-Song, Shibata Yukimasa, Nishiwaki Kiyoji

Abstract excerpt

During development of the Caenorhabditis elegans gonad, the gonadal leader cells, called distal tip cells (DTCs), migrate in a U-shaped pattern to form the U-shaped gonad arms. The ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) family metalloproteases MIG-17 and GON-1 are required for correct DTC migration. Mutations in mig-17 result in misshapen gonads due to the misdirected DTC migration,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Calcium-Binding Proteins

Share to Collagen Type IV

Share to Enhancer Elements, Genetic

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Identifiers

PMID: 33264296
DOI: 10.1371/journal.pone.0240571
PMCID: PMC7710118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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