Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV.

Development (Cambridge, England) - 1 May 2009

Kawano Takehiro, Zheng Hong, Merz David C, Kohara Yuji, Tamai Katsuyuki K, Nishiwaki Kiyoji, Culotti Joseph G

Abstract excerpt

The gonad arms of C. elegans hermaphrodites acquire invariant shapes by guided migrations of distal tip cells (DTCs), which occur in three phases that differ in the direction and basement membrane substrata used for movement. We found that mig-6 encodes long (MIG-6L) and short (MIG-6S) isoforms of the extracellular matrix protein papilin, each required for distinct aspects of DTC migration. Both MIG-6 isoforms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type IV

Share to Extracellular Matrix Proteins

Share to Glycoproteins

Share to Gonads

Share to Metalloendopeptidases

Share to Protein Isoforms

Source

Open in PubMed Open full text

Identifiers

PMID: 19297413
DOI: 10.1242/dev.028472
PMCID: PMC2674254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C. elegans mig-6 encodes papilin isoforms that affect distinct aspects of DTC migration, and interacts genetically with mig-17 and collagen IV.PMID 19297413Read ↗

Genetic interactions among ADAMTS metalloproteases and basement membrane molecules in cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

Genetics of extracellular matrix remodeling during organ growth using the Caenorhabditis elegans pharynx model.Semantic proximity Read ↗

The novel secreted factor MIG-18 acts with MIG-17/ADAMTS to control cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

MIG-17/ADAMTS controls cell migration by recruiting nidogen to the basement membrane in C. elegans.Semantic proximity Read ↗

Mutations in fibulin-1 and collagen IV suppress the short healthspan of mig-17/ADAMTS mutants in Caenorhabditis elegans.Semantic proximity Read ↗

Organ Length Control by an ADAMTS Extracellular Protease in Caenorhabditis elegans.Semantic proximity Read ↗

An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans.Semantic proximity Read ↗

A fibulin-1 homolog interacts with an ADAM protease that controls cell migration in C. elegans.Semantic proximity Read ↗

A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans.Semantic proximity Read ↗

Tissue architecture in the Caenorhabditis elegans gonad depends on interactions among fibulin-1, type IV collagen and the ADAMTS extracellular protease.Semantic proximity Read ↗

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans.Semantic proximity Read ↗

C. elegans ten-1 is synthetic lethal with mutations in cytoskeleton regulators, and enhances many axon guidance defective mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.