Article
A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans.
Science (New York, N.Y.) - 23 Jun 2000
Nishiwaki K, Hisamoto N, Matsumoto K
Abstract excerpt
In Caenorhabditis elegans, the gonad acquires two U-shaped arms by the directed migration of its distal tip cells (DTCs) along the body wall basement membranes. Correct migration of DTCs requires the mig-17 gene, which encodes a member of the metalloprotease-disintegrin protein family. The MIG-17 protein is secreted from muscle cells of the body wall and localizes in the basement membranes of gonad. This...
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