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Article

Polymorphisms of human aryl hydrocarbon receptor (AhR) gene in a French population: relationship with CYP1A1 inducibility and lung cancer.

Carcinogenesis - 1 Nov 2001

Cauchi S, Stücker I, Solas C, Laurent-Puig P, Cénée S, Hémon D, Jacquet M, Kremers P, Beaune P, Massaad-Massade L

Abstract excerpt

The Ah receptor (AhR) is a ligand-dependent transcription factor that positively regulates the expression of the CYP1A1 gene. We investigated the genetic polymorphisms of the AhR gene including the promoter, and examined the link between these polymorphisms, CYP1A1 inducibility and the lung cancer incidence. The AhR promoter region and the 11 exons of 30 subjects were screened. Among the three polymorphisms...

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PMID: 11698344
DOI: 10.1093/carcin/22.11.1819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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