Human Ah receptor (AHR) gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility.

doi:10.1097/00008571-199704000-00002

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Article

Human Ah receptor (AHR) gene: localization to 7p15 and suggestive correlation of polymorphism with CYP1A1 inducibility.

Pharmacogenetics - 1 Apr 1997

Micka J, Milatovich A, Menon A, Grabowski G A, Puga A, Nebert D W

Abstract excerpt

The mammalian aromatic hydrocarbon receptor (AHR) is a ubiquitous ligand-activated transcription factor. AHR ligands include 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; dioxin), benzo[a]pyrene, and polychlorinated and polybrominated biphenyls; the endogenous ligand is not yet known. Following liga...

Topics

Amino Acid Sequence
Chromosome Mapping
Chromosomes, Human, Pair 7
Cytochrome P-450 CYP1A1
Female
Humans
In Situ Hybridization, Fluorescence
Lod Score
Male
Molecular Sequence Data
Pedigree
Phenotype
Polymorphism, Genetic
Receptors, Aryl Hydrocarbon

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PMID: 9170146
DOI: 10.1097/00008571-199704000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9170146-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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