Article
Polymorphisms of human Ah receptor gene are not involved in lung cancer.
Pharmacogenetics - 1 Jun 1995
Kawajiri K, Watanabe J, Eguchi H, Nakachi K, Kiyohara C, Hayashi S
Abstract excerpt
The Ah receptor (Ahr) is a ligand-dependent transcription factor that positively regulates inducible expression of the CYP1A1 gene. Based on the sequence information of the human Ahr and the intron-exon junctions of the mouse counterpart, an analysis of single-strand conformational polymorphism (SSCP) was carried out to detect subtle base differences in the coding region of the gene among individuals. We found...
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