Article
T cell responses in HIV type 1-infected adolescent minorities share similar epitope specificities with whites despite significant differences in HLA class I alleles.
AIDS research and human retroviruses - 1 Nov 2003
Bansal Anju, Sabbaj Steffanie, Edwards Bradley H, Ritter Doug, Perkins Christopher, Tang James, Szinger James J, Weiss Heidi, Goepfert Paul A, Korber Bette, Wilson Craig M, Kaslow Richard A, Mulligan Mark J
Abstract excerpt
African-Americans (AFAM) and Hispanics (HIS) represent only 13% and 12% of the U.S. population but 54% and 19%, respectively, of annually incident HIV-1 infections in the United States. The 88 patients in the current study were from U.S. racial or ethnic minority groups (72% African-American, 17% Hispanic), female (85%), and adolescent (mean age 20 years). Their HLA allele distributions were distinct from...
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