Article
Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians.
AIDS research and human retroviruses - 1 May 2004
Yu Xu G, Addo Marylyn M, Perkins Beth A, Wej Feili, Rathod Almas, Geer Shaun C, Parta Mark, Cohen Daniel, Stone David R, Russell Christopher J, Tanzi Giancarlo, Mei Shan, Wurcel Alysse G, Frahm Nicole, Lichterfeld Mathias, Heath Laura, Mullins James I, Marincola Francesco, Goulder Philip J R, Brander Christian, Allen Todd, Cao Yunzhen, Walker Bruce D, Altfeld Marcus
Abstract excerpt
China is a region of the world with a rapidly spreading HIV-1 epidemic. Studies providing insights into HIV-1 pathogenesis in infected Chinese are urgently needed to support the design and testing of an effective HIV-1 vaccine for this population. HIV-1-specific T cell responses were characterized in 32 HIV-1-infected individuals of Chinese origin and compared to 34 infected caucasians using 410 overlapping...
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