Article
Population coverage by HLA class-I restricted cytotoxic T-lymphocyte epitopes.
Immunogenetics - 1 Jan 2001
Longmate J, York J, La Rosa C, Krishnan R, Zhang M, Senitzer D, Diamond D J
Abstract excerpt
Vaccination using cytotoxic T-lymphocyte (CTL) epitopes has become a widely used immunization strategy, especially because their structure makes them an attractive alternative to the delivery of whole proteins as immunogens. Nonetheless, their use is limited, in particular because of their specificity, being recognized only by cognate HLA alleles. The potential for immunizing a substantial portion of an...
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