Article
Intraspecies heterogeneity of immunoglobulin alpha-chain constant region genes in rhesus macaques.
Immunology - 1 Aug 2001
Scinicariello F, Attanasio R
Abstract excerpt
Immunoglobulin A (IgA) is the major antibody class present in external secretions and is also an important component of serum immunoglobulins. On mucosal surfaces, IgA represents a first line of defence by neutralizing invading pathogens. The number of IgA constant-region genes (C alpha) present in different mammalian species is variable. Immunoglobulin C alpha genes differ mainly in the sequences located in the...
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