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Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles.

Immunity - 9 Feb 2021

Vázquez Bernat Néstor, Corcoran Martin, Nowak Izabela, Kaduk Mateusz, Castro Dopico Xaquin, Narang Sanjana, Maisonasse Pauline, Dereuddre-Bosquet Nathalie, Murrell Ben, Karlsson Hedestam Gunilla B

Abstract excerpt

Definition of the specific germline immunoglobulin (Ig) alleles present in an individual is a critical first step to delineate the ontogeny and evolution of antigen-specific antibody responses. Rhesus and cynomolgus macaques are important animal models for pre-clinical studies, with four main sub-groups being used: Indian- and Chinese-origin rhesus macaques and Mauritian and Indonesian cynomolgus macaques. We...

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PMID: 33484642
DOI: 10.1016/j.immuni.2020.12.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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