Back to search

Article

Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoires

2018-01-29

Abstract excerpt

The Rhesus macaque is a valuable preclinical animal model to estimate vaccine effectiveness, and is also important for understanding antibody maturation and B-cell repertoire evolution responding to vaccination; however, incomplete mapping of rhesus immunoglobulin germline genes hinders the research efforts. To address this deficiency, we sequenced B-cell receptor (BCR) repertoires of 75 India Rhesus macaques. Usi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7598222c-f8ba-5ff4-b7e1-9c1a51b4b12d
DOI
10.1101/254599
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of Variable and Joining germline genes and alleles for Rhesus macaque from B-cell receptor repertoiresDOI 10.1101/254599
A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus MacaquesSemantic proximity
Population-level genomic analysis of immunoglobulin loci variation in rhesus macaques reveals extensive germline diversity.Semantic proximity
Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles.Semantic proximity
Systematic profiling of full-length immunoglobulin and T-cell receptor repertoire diversity in rhesus macaque through long read transcriptome sequencingSemantic proximity
Addressing IGHV Gene Structural Diversity Enhances Immunoglobulin Repertoire Analysis: Lessons From Rhesus MacaqueSemantic proximity
Genetic divergence of the rhesus macaque major histocompatibility complex.Semantic proximity
Necessity of individual VDJ-databases for annotating antibody heavy chain characteristics in non-human primates.Semantic proximity
Single cell based high-throughput Ig and TCR repertoire sequencing analysis in rhesus macaquesSemantic proximity
Integrative Curation of Human and Rhesus Macaque Immunoglobulin Germline Loci for Population-Scale Immunogenomics 2267549Semantic proximity
Immunoglobulin light-chain genes in the rhesus macaque I: kappa light-chain germline sequences for subgroups IGKV1, IGKV and IGKV3.Semantic proximity
Immunoglobulin light-chain genes in the rhesus macaque II: lambda light-chain germline sequences for subgroups IGLV1, IGLV2, IGLV3, IGLV4 and IGLV5.Semantic proximity
A comparison of human and macaque (Macaca mulatta) immunoglobulin germline V regions and its implications for antibody engineering.Semantic proximity
Select a neighboring publication to make it the new centre.