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Article

A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans.

Cell - 12 Dec 2003

Davies Andrew G, Pierce-Shimomura Jonathan T, Kim Hongkyun, VanHoven Miri K, Thiele Tod R, Bonci Antonello, Bargmann Cornelia I, McIntire Steven L

Abstract excerpt

The activities of many neuronal proteins are modulated by ethanol, but the fundamental mechanisms underlying behavioral effects of ethanol remain unclear. To identify mechanisms responsible for intoxication, we screened for Caenorhabditis elegans mutants with altered behavioral responses to ethanol. We found that slo-1 mutants, which were previously recognized as having slightly uncoordinated movement, are highly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 14675531
DOI: 10.1016/s0092-8674(03)00979-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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