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Article

The SLO-1 BK channel of Caenorhabditis elegans is critical for muscle function and is involved in dystrophin-dependent muscle dystrophy.

Journal of molecular biology - 28 Apr 2006

Carre-Pierrat Maité, Grisoni Karine, Gieseler Kathrin, Mariol Marie-Christine, Martin Edwige, Jospin Maelle, Allard Bruno, Ségalat Laurent

Abstract excerpt

The Caenorhabditis elegans SLO-1 channel belongs to the family of calcium-activated large conductance BK potassium channels. SLO-1 has been shown to be involved in neurotransmitter release and ethanol response. Here, we report that SLO-1 also has a critical role in muscles. Inactivation of the slo-1 gene in muscles leads to phenotypes similar to those caused by mutations of the dystrophin homologue dys-1....

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Identifiers

PMID: 16527307
DOI: 10.1016/j.jmb.2006.02.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The SLO-1 BK channel of Caenorhabditis elegans is critical for muscle function and is involved in dystrophin-dependent muscle dystrophy.PMID 16527307Read ↗

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