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Article

A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans.

PloS one - 3 May 2010

Mitchell Philippa, Mould Richard, Dillon James, Glautier Steven, Andrianakis Ioannis, James Christopher, Pugh Amanda, Holden-Dye Lindy, O'Connor Vincent

Abstract excerpt

Prolonged alcohol consumption in humans followed by abstinence precipitates a withdrawal syndrome consisting of anxiety, agitation and in severe cases, seizures. Withdrawal is relieved by a low dose of alcohol, a negative reinforcement that contributes to alcohol dependency. This phenomenon of 'w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20454655
DOI: 10.1371/journal.pone.0010422
PMCID: PMC2862703

Genes

NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20454655-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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