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Article

Susceptibility to ethanol withdrawal seizures is produced by BK channel gene expression.

Addiction biology - 1 May 2014

Ghezzi Alfredo, Krishnan Harish R, Atkinson Nigel S

Abstract excerpt

Alcohol withdrawal seizures are part of the symptomatology of severe alcohol dependence and are believed to originate from long-term neural adaptations that counter the central nervous system depressant effects of alcohol. Upon alcohol withdrawal, however, the increased neural excitability that was adaptive in the presence of alcohol becomes counter-adaptive and produces an imbalanced hyperactive nervous system....

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Identifiers

PMID: 22734584
DOI: 10.1111/j.1369-1600.2012.00465.x
PMCID: PMC4860885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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