Article
Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.
Carcinogenesis - 1 Sept 2007
Yamada Hidetaka, Shinmura Kazuya, Okudela Koji, Goto Masanori, Suzuki Masaya, Kuriki Ken, Tsuneyoshi Toshihiro, Sugimura Haruhiko
Abstract excerpt
Germ line mutations of the p53 gene are known to cause Li-Fraumeni syndrome, and a germ line p53 mutation has recently been reported in a small subset of familial gastric cancer (FGC) in Europe and Korea. Although the incidence of gastric cancer is very high in Japan and familial clustering is no...
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