Article
Evolution in Saccharomyces cerevisiae: identification of mutations increasing fitness in laboratory populations.
Genetics - 1 Nov 2003
Blanc Victoria M, Adams Julian
Abstract excerpt
Since the publication of the complete sequence of the genome of Saccharomyces cerevisiae, a number of comprehensive investigations have been initiated to gain insight into cellular function. The focus of these studies has been to identify genes essential for survival in specific environments or those that when mutated cause gross phenotypic defects in growth. Here we describe Ty1-based mutational approaches...
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