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Article

Evolution in Saccharomyces cerevisiae: identification of mutations increasing fitness in laboratory populations.

Genetics - 1 Nov 2003

Blanc Victoria M, Adams Julian

Abstract excerpt

Since the publication of the complete sequence of the genome of Saccharomyces cerevisiae, a number of comprehensive investigations have been initiated to gain insight into cellular function. The focus of these studies has been to identify genes essential for survival in specific environments or those that when mutated cause gross phenotypic defects in growth. Here we describe Ty1-based mutational approaches...

Topics

Amino Acid Sequence
Base Sequence
Biological Evolution
DNA Primers
DNA, Fungal
Genetic Variation
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae
Sequence Homology, Nucleic Acid

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Identifiers

PMID: 14668358
DOI: 10.1093/genetics/165.3.975
PMCID: PMC1462841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-14668358-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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