Article
Functional analysis of the genes of yeast chromosome V by genetic footprinting.
Science (New York, N.Y.) - 20 Dec 1996
Smith V, Chou K N, Lashkari D, Botstein D, Brown P O
Abstract excerpt
Genetic footprinting was used to assess the phenotypic effects of Ty1 transposon insertions in 268 predicted genes of chromosome V of Saccharomyces cerevisiae. When seven selection protocols were used, Ty1 insertions in more than half the genes tested (157 of 268) were found to result in a detectable reduction in fitness. Results could not be obtained for fewer than 3 percent of the genes tested (7 of 268)....
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