Article
Increased calcium influx through acetylcholine receptors in dunce neurons.
The International journal of neuroscience - 1 Jan 2004
Alshuaib Waleed B, Hasan Mohamed, Cherian Susan P, Fahim Mohamed A
Abstract excerpt
Calcium homeostasis was studied in dunce, a Drosophila mutant that is defective in learning and memory. Fura 2-AM fluorescence photometry was used to measure the intracellular calcium concentration in wild type and dunce cleavage-arrested neurons under resting conditions and in response to neurotransmitters. After acetylcholine application, the peak [Ca2+]i was greater in dunce (693 +/- 125 nM) than in wild type...
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