Article
A cyclic AMP-activated K+ channel in Drosophila larval muscle is persistently activated in dunce.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jan 1991
Delgado R, Hidalgo P, Diaz F, Latorre R, Labarca P
Abstract excerpt
Single-channel recording from longitudinal ventrolateral Drosophila larval muscle reveals the presence of a potassium-selective channel that is directly and reversibly activated by cAMP in a dose-dependent fashion. Activation is specific and it cannot be mimicked by a series of agents that include AMP, cGMP, ATP, inositol trisphosphate, and Ca2+. Channel current records obtained from larval muscle in different...
Topics
- 8-Bromo Cyclic Adenosine Monophosphate
- Animals
- Cyclic AMP
- Cyclic GMP
- Drosophila
- Larva
- Membrane Potentials
- Muscles
- Mutation
- Potassium Channels