Article
Capn10, a candidate gene responsible for type 2 diabetes mellitus in the OLETF rat.
IUBMB life - 1 Sept 2003
Muramatsu Youji, Taniguchi Yukio, Kose Hiroyuki, Matsumoto Kozo, Yamada Takahisa, Sasaki Yoshiyuki
Abstract excerpt
The rat strain Otsuka Long-Evans Tokushima Fatty (OLETF) is an animal model for type 2 diabetes mellitus. Nidd8/of has been identified as one of 14 quantitative trait loci (QTLs) involved in the diabetes by a whole genome search in 160 F2 progenies obtained by mating the OLETF and F344 rats. Comparative mapping between human and rat indicated that the Nidd8/of genomic region, near D9rat21 on rat chromosome 9,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
