Article
Role of calpain-10 in the development of diabetes mellitus and its complications.
Archives of medical research - 1 Feb 2014
Pánico Pablo, Salazar Ana María, Burns Anna L, Ostrosky-Wegman Patricia
Abstract excerpt
Calpain activity has been implicated in several cellular processes such as cell signaling, apoptosis, exocytosis, mitochondrial metabolism and cytoskeletal remodeling. Evidence has indicated that the impairment of calpain expression and the activity of different calpain family members are involved in diverse pathologies. Calpain-10 has been implicated in the development of type 2 diabetes, and polymorphisms in...
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