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Article

<i>In vitro</i> selection of <i>Plasmodium falciparum</i> 3D7 for expression of variant surface antigens associated with severe malaria in African children

1 Aug 2003

Abstract excerpt

P. falciparum-infected red blood cells (IRBC) can adhere to endothelial host receptors through parasite-encoded, clonally variant surface antigens (VSA). The VSA-mediated IRBC adhesion and the acquired VSA-specific antibody response have both been linked to IRBC organ tropism and disease severity. Parasites isolated from young children with severe malaria (SM) tend to express a limited and conserved set of VSA...

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PMID: 14651589
DOI: 10.1111/j.1365-3024.2003.00652.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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